Management of Multiple Drug-Resistant Infections
Humana Press, Totowa,
S. H. Gillespie, Ed.,
NJ, USA, 2004,
This is a timely volume for, despite efforts to mitigate antibiotic use and selection pressure, the incidence of multi-resistant infections continues to increase in many centres and countries. The book has 21 well-written chapters, largely organized by pathogen species. The organisms thus covered include pneumococci in pneumonia and meningitis, glycopeptide-resistant Staphylococcus aureus, glycopeptide-resistant enterococci, multi-resistant Acinetobacter spp., Helicobacter pylori, Neisseria gonorrhoeae, Salmonella spp., Burkholderia spp., Mycobacterium tuberculosis, other mycobacteria, Candida spp., amphotericin-resistant fungi, Plasmodium spp., schistosomes, human immunodeficiency virus and cytomegalovirus. Two chapters—one on resistant urinary infections and the other on infection control for MRSA—break this organizational mould. Some chapters stick tightly to the clinical management of multi-resistant infections whereas others contain large sections on the relevant resistance epidemiology and mechanisms, along with advice on detecting resistance in the laboratory. All are very thoroughly referenced. One limitation, which stems from this organization, is a degree of duplication. Thus, linezolid and quinupristin/dalfopristin are discussed in almost every chapter relating to a Gram-positive pathogen.