Gene Transfer to Animal Cells
by Richard Twynman
Edition: 1st., 2005
The Adanced Methods series is intended for advanced undergraduates,
graduate students and established research scientists. Titles in the
series are designed to cover current important areas of research in
life sciences, and include both theoretical background and detailed
protocols. The aim is to give researchers sufficient theory, supported
by references, to take the given protocols and adapt them to their
particular experimental systems.
transfer to animal cells was first achieved more than 30 years ago.
Since then, transformation technology has developed rapidly, resulting
in a multitude of techniques for cell transformation and the creation
of transgenic animals. As with any expanding technology, it becomes
difficult to keep track of all the developments and to find a concise
and comprehensive source of information that explains all the
underlying principles. Gene Transfer to Animals Cells describes the
principles behind gene transfer technologies, how gene expression is
controlled in animal cells and how advanced strategies can be used to
add, exchange or delete sequences from animal genomes in a conditional
manner. The final chapter provides an overview of all the applications
of animal cell transformation in farming, medicine and research.