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Thread: Gene Vaccines

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    Default Gene Vaccines

    GENE VACCINES
    Josef Thalhamer, Richard Weiss and Sandra Scheiblhofer
    (Editors)



    displayimage.jpg

    Pages: 330, 49 illus.
    Publisher:
    Edition: 1th ed. 2012
    Language: English
    ISBN: 978-3-7091-0438-5
    Format: PDF
    Size: 5,2 MB

    Description

    Presents the only updated volume on gene vaccines
    Focuses on the most promising approaches towards gene vaccination close to or already in clinical use
    Provides an objective comparison of different methods and protocols

    The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.


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    Last edited by Motoko; 27th April 2012 at 01:34 AM. Reason: ADD VISIBLE IMAGE. ARRANGE INFO.
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    Default Re: Gene Vaccines

    Re-upload, please.
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