The Science and Applications of Synthetic and Systems Biology

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The Science and Applications of Synthetic and Systems Biology
by Eileen Choffness, David Rellman and Leslie Pray





Pages: 571
Publisher: NAS Press
Edition: 2011
Language: English
ISBN: 9780309219396
Format: PDF
Size: 32 MB

Description

This issue explores the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases.

Participants discussed how these advanced technologies have the potential to improve understanding of infectious microbes and the mechanisms by which they cause disease; the applications of these tools and approaches for disease detection and diagnostic platforms; and the development of new therapeutics, vaccines, and other infectious disease intervention technologies.

Contents
Workshop Overview
Workshop Overview References
Appendixes
A Contributed Manuscripts
A1 Commercial Applications of Synthetic Biology
A2 Synthetic Biology: Applications Come of Age
A3 The Genome as the Unit of Engineering
A4 Synthetic Biology—A New Generation of Biofilm Biosensors
A5 Synthetic Biology and the Art of Biosensor Design
A6 Systems Analysis of Adaptive Immunity by Utilization of High-Throughput Technologies
A7 The New Science of Sociomicrobiology and the Realm of Synthetic and Systems Ecology
A8 Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
A9 Synthetic Biology “From Scratch"
A10 Manufacturing Molecules Through Metabolic Engineering
A11 Novel Approaches to Combat Biofilm Drug Tolerance
A12 Next-Generation Synthetic Gene Networks
A13 Engineering Scalable Biological Systems
A14 Metabolic Systems Biology
A15 Systems Vaccinology
A16 Solving Vaccine Mysteries: A Systems Biology Perspective
A17 Systems Biology of Vaccination for Seasonal Influenza in Humans
A18 Synthetic Systems as Microbial Threats: Predictability of Loss-of-Function Mutations in Engineered Systems
A19 Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
A20 Programming Cells: Towards an Automated ‘Genetic Compiler'
A21 Prokaryotic Gene Clusters: A Rich Toolbox for Synthetic Biology
A22 The Silicon Trypanosome
B Agenda
C Acronyms
D Glossary
E Forum Member Biographies
F Speaker Biographies

Source: ul.to - MediaFire

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