by A. Ruvinsky and J. A. Marshall Graves
Edition: 1st., 2005
Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse, and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion, and lab animals. Contributors include leading researchers from Europe, the U.S., Australia, and Japan, to provide a major reference work. The book covers structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, the transcriptome, the proteome, evolution of DNA sequences, comparative chromosome mapping and painting, genome analysis and bioinformatics, genome databases, gene prediction and the use of genomic information to understand inherited diseases, pharmacogenomics, and mammalian population genetics and genomics.