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Thread: The Third Histamin Receptor, 1st Edition (2009)

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    Default The Third Histamin Receptor, 1st Edition (2009)

    The Third Histamin Receptor
    Selective Ligands as Potential Therapeutic Agents in CNS Disorders
    ByDivya Vohora





    PAGES:
    385
    PUBLISHER:
    CRC PressINC
    EDITION:
    1st Edition (2009)
    LANGUAGE: English
    ISBN-10: 1420053922
    ISBN-13: 978-1420053920



    Description:

    The third histamine receptor, identified in 1983, generated widespread interest as a potential target for its extensive role in the central nervous system (CNS). The first book on this subject, edited by Leurs and Timmerman, was available in 1998. However, many advances have taken place since then. Molecular advances in the past few years followed by cloning of human H3 receptors and development of a large number of selective and nonimidazole H3 receptor antagonists with pharmacological evidence in a number of different therapeutic conditions raise the hope for having an H3 receptor-related drug to hit the market soon. In this book, an attempt has been made to bring together worldwide scientists actively involved in the H3 field both from academia and from pharmaceutical industry including medicinal and computational chemists, biologists, and pharmacologists. This book aims to provide a single source of information from the identification and localization of H3 receptor to the development of novel ligands incorporating preclinical and more recent clinical studies, indicating the earliest possible stage of development of these ligands. It is a blend of almost all the therapeutic activities being explored for these ligands with literature from studies using cutting-edge research techniques as well as patent literature.


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