Welcome to Veterinary Medicine Electronic Library

Your Destination for Most Unique Veterinary Resources

  •  » If You're Vet Student & Searching For Educational Stuff
  •  » You're Researcher Looking For Articles & Journals
  •  » You're a Veterinarian & You Want to Improve Your Skills
  •  » You're a Pet Owner Looking For a Guide

...then you have come to the right place!

we will try to help you with your needs.

YES! I want to register an account for free right now!

N.B.: Our Services are Free of Charge, because; Knowledge must be free

NOTICE Notice: This is an old thread. The last post was 1393 days ago. If your post is not directly related to this discussion please consider making a new thread.
Results 1 to 1 of 1

Thread: Mucosal_Vaccines_Modern_Concepts,_Strategies,_and_ Challenges__2012

  1. #1
    midozinger's Avatar
    New Member

    Join Date
    Dec 2010
    Small Animals Practice
    Total Posts
    Rep Power
    Total thanks received
    Thanks for this post
    Small Animals Practice I'm from Egypt

    Default Mucosal_Vaccines_Modern_Concepts,_Strategies,_and_ Challenges__2012

    Mucosal Vaccines: Modern Concepts, Strategies, and Challenges
    by Pamela A. Kozlowski

    Book Description

    This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.

    Product Details

    • Hardcover: 208 pages
    • Publisher: ; 2012 edition (January 11, 2012)
    • Language: English
    • ISBN-10: 3642236928
    • ISBN-13: 978-3642236921
    • Hidden contents (Our Amazon affiliate links)
      You must click 'Thank You' before you can see the data contained here. You can purchase this item from Amazon with discount through our amazon affiliate link.
      BUT You DONOT have sufficient rights to see the hidden data contained here.
      Please Register to see contents.

    Last edited by Motoko; 31st December 2012 at 04:37 AM. Reason: ADD VISIBLE IMAGE.
    Reply With Quote Reply With Quote

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

About VET E-Lib

    Your Destination for Most Unique Veterinary Resources. If You're Vet Student & Searching For Educational Stuff, if you're Researcher Looking For Articles & Journals, if you're a Veterinarian & You Want to Improve Your Skills, if you're a Pet Owner Looking For a Guide, then you have come to the right place! and we will try to help you with your needs.

Quick Links

Follow us on

Facebook youtube Twitter RSS Feed Email Us