Practical Weight Management in Dogs and Cats
by Todd Towell
Edition: 1st., 2011
The last decade has seen a fundamental shift in our understanding of obesity. The discovery of hormones and cytokines generated by adipose tissue (termed adipokines) has expanded fat’s traditional roles as an energy storage depot, insulator, and support for abdominal organs. Fat is
now recognized as the most abundant source of hormones in the body, making it the largest endocrine organ.
Additionally, macrophages in adipose tissue contribute to the release of numerous inflammatory cytokines and other adipokines into the blood. As a result, overweight and obese individuals reside in a state of chronic inflammation.