Bone and Development
Topics in Bone Biology
by Felix Brooner

Pages: 321
Publisher: --
Edition: 1st., Vol. 6, 2010
Serie: Topics in Bone Biology
Language: English
ISBN: 978-1848828216


This book, Vol. 6 in the series Topics in Bone Biology, deals with bone development from growth to mineralization. Understanding tissue development involves combining embryological and histological information with the increasing knowledge from molecular and genetic studies. In each developmental stage, some genes are expressed and others silenced. Disease, especially disease progression, also is characterized by changes in gene expression that then are transmitted to daughter cells. In both situations, the choreography of gene expression and partial or complete silencing often are the result of the interaction between the genome and the epigenome, i.e., between a very stable set of structures and rapidly changing environmental factors.

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