Animal Models of Neurological Disease, I Neurodegenerative Diseases
by Alan Boulton
Edition: 1st., 1992
Serie: Neuromethods, Vol. 21
The use of animal models continues to be the most reliable way of studying pathophysiologic mechanisms as well as treatments for neurological disorders. In two companion volumes, Animal Models of Neurological Disease highlights new information and techniques available in this rapidly growing area.
This volume of Neuromethods focuses on commonly studied neurodegenerative diseases, highlighting the similarities and differences between the human condition and that obtained using animal models. Chapters are contributed by experts in the field and cover a variety of topics, including: the ethics of using animal models • Alzheimer's disease • Huntington's disease • Parkinson's disease • Lesch-Nyhan disease • genetic and nongenetic demyelinating diseases • cerebellar ataxias • rodent and primate models • surgical lesions • neurotoxins.