Leukemias: Principles and Practice of Therapy
by Stefan Faderl and Hagop Kantarjian

Pages: 456
Publisher: --
Edition: 2010
Language: English
ISBN: 1405182350

Edited by experts from one of the world’s largest leukemia centers, this book provides information on the biology of the variety of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the future and explain the rationale for ongoing clinical trials.Topics include:

  • Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors, BCR-ABL inhibitors)
  • Ras inhibitors
  • Epigenetic therapy (hypomethylaters and histone deacetylase inhibitors)
  • Lenalidomide analogs
  • New chemotherapy drugs, e.g. clofarabine, cloretazine, sapacitabine, forodesine
  • Combinations of chemotherapy with kinase inhibitors (e.g. ALL induction protocols in combination with dasatinib or imatinib)
  • New monoclonal antibodies (lumiliximab, humaxCD20, anti-CD40)
  • Thrombopoietic agents

Leukemias: Principles and Practice of Therapy

  • Includes practical information to guide you in challenging situations, such as treatment of elderly patients, pregnancy, relapsed and refractory disease
  • Incorporates chapters on supportive care and pharmacologic information about the most frequently used drugs in this area

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