Handbook of Animal Models of Infection:
Experimental Models in Antimicrobial Chemotherapy
Merle A. Sande (Author), Oto Zak (Editor)
Hardcover: 1136 pages
Publisher: Academic Press; 1st edition (June 22, 1999)
Book Description: Handbook of Animal Models of Infection is a complete
revision of a three-volume text that was published in 1986.
It incorporates the major advances in the field during the
past decade, in particular those concerning molecular
biological procedures and new models that have been
developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise.
The book is divided into five sections; the first covering
the general methodologies, followed by sections describing
experimental bacterial, mycotic, parasitic, and viral
* Discusses ethical and safety aspects in an introductory background section
* Covers principles of animal care and current techniques appropriate for the use of animal models of infection
* Details a wide range of animals including rodents, rabbits, cats, and primates
* Provides hands-on descriptions of how to set up the model
* Discusses the major advantages and limitations of each model
* Ensures full coverage of bacterial, fungal, viral, and parasitic infections
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