Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions

Edited by: Jeremy Brown, Sven Hammerschmidt and Carlos Orihuela


Pages: 458
Publisher: Inc.
Edition: 2015
Language: English
ISBN: 978-0-12-410530-0

Streptococcus pneumoniae (the pneumococcus) has been and continues to be among the chief causes of human misery and death. It is capable of a broad swath of disease manifestations, including otitis media, the more serious community-acquired pneumonia, and devastating illnesses such as septicemia and meningitis. As a commensal colonizer of the nasopharynx, the pneumococcus is the prototypical opportunistic pathogen, but it is also capable of causing disease in previously seemingly healthy individuals. While the overall attack rate for the pneumococcus is low, so many individuals are colonized that the global burden of disease is enormous.

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