2 volume set
Author: David M Knipe
Publisher: Lippincott Williams & Wilkins
Edition: Fifth edition (January 1, 2006)
Size: 89.41 MB
In the early 1980s, Bernie Fields originated the idea of a virology reference textbook that combined the molecular aspects of viral replication with the medical features of viral infections. This broad view of virology reflected Bernie's own research, which applied molecular and genetic analyses to the study of viral pathogenesis, providing an important part of the foundation for the field of molecular pathogenesis. Bernie led the publication of the first three editions of, Virology.
Unfortunately, we lost Bernie to pancreatic cancer soon after the third edition went into production. The third edition became Fields Virology in his memory, and it is fitting that the book continues to carry his name.
We have retained the general organization of the first four editions for the fifth edition of Fields Virology. Section I contains chapters on general aspects of virology, and Section II contains chapters on replication and medical aspects of specific virus families and specific viruses of medical importance. Nearly all of the chapters have been updated to reflect the rapid advances in virology during the past 6 years. In addition, in Section I, we have added new chapters on emerging viruses and viruses of protists. In Section II, we have greatly expanded the coronavirus chapter to describe the SARS virus. The orthomyxovirus chapter has been expanded to include avian influenza and other emerging influenza virus strains. For some virus families, we have combined the medical and replication chapters into a single chapter to eliminate duplication and to present a more coherent presentation of that specific virus or virus family. The main emphasis continues to be on viruses of medical importance and interest, but other viruses are described in specific cases where more is known about their mechanisms of replication or pathogenesis. Although not formally viruses, prions are still included in this edition for historical reasons and because of the intense interest in the infectious spongiform encephalopathies.