NOTICE Notice: This is an old thread. The last post was 1807 days ago. If your post is not directly related to this discussion please consider making a new thread.
Results 1 to 2 of 2

Thread: Epigenetics and Disease: Pharmaceutical Opportunities (Progress in Drug Research)

  1. #1
    dell's Avatar
    Junior Member


    Status
    Offline
    Join Date
    Sep 2009
    Work
    Large Animals Practice
    Country
    India
    Gender
    Male
    Total Posts
    41
    Rep Power
    0
    Total thanks received
    943
    Thanks for this post
    27
    Large Animals Practice I'm from India

    Default Epigenetics and Disease: Pharmaceutical Opportunities (Progress in Drug Research)

    Epigenetics and Disease. Pharmaceutical Opportunities
    by Susan Gasser



    Pages: 281
    Publisher: --
    Edition:
    1st., 2010
    Language: English
    ISBN: 978-3764389885


    Description

    Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders. Recent biomedical interest in this regulatory system stems from the fact that epigenetic, in contrast to genetic, alterations are in principle amenable to pharmacological intervention. A few epigenetically active drugs, for example histone deacetylase inhibitors (HDACi) and DNA methyltransferase (DNMT) inhibitors, have been approved by FDA for treatment of cancers such as CTCL, MDS, and AML. This volume explores the scientific background for clinical applications of epigenetically active drugs. Included are descriptions of epigenetic controls over gene expression, the post-transcriptional silencing of genes by RNA interference (RNAi) and microRNAs, as well as new findings from stem cell research which are relevant to pharmacological applications.

    Enjoy!



    Last edited by Motoko; 16th January 2013 at 10:37 PM. Reason: ADD INFO, IMAGE, DESCRIPTION.
    Reply With Quote Reply With Quote
    Thanks

  2. #2
    Micotil's Avatar
    Banned


    Status
    Offline
    Join Date
    Nov 2010
    Work
    Large Animals Practice
    Country
    Palestine
    Gender
    Male
    Total Posts
    912
    Rep Power
    0
    Total thanks received
    71,522
    Thanks for this post
    33
    Large Animals Practice I'm from Palestine

    Arrow Epigenetics and Disease: Pharmaceutical Opportunities (Progress in Drug Research)

    2010


    Hidden contents (Our Amazon affiliate links)
    You must click 'Thank You' before you can see the data contained here. You can purchase this item from Amazon with discount through our amazon affiliate link.
    BUT You DONOT have sufficient rights to see the hidden data contained here.
    Please Register to see contents.
    Reply With Quote Reply With Quote
    Thanks

Similar Threads

  1. Furunculosis: Multidisciplinary Fish Disease Research
    By Tomajwwii in forum AquaCulture & Fish eBooks
    Replies: 1
    Last Post: 10th November 2013, 09:47 PM
  2. Animal Agriculture Research Progress
    By mguzel in forum Livestock Nutrition, Management & Welfare
    Replies: 2
    Last Post: 4th March 2013, 05:10 PM
  3. [Parasitology] Progress in Parasitology (Parasitology Research Monographs Vol. 2) 2011
    By Micotil in forum Basic Veterinary eBooks
    Replies: 1
    Last Post: 22nd May 2012, 10:53 PM
  4. Replies: 3
    Last Post: 23rd December 2011, 05:26 AM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •