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Thread: Immunology, Phenotype First: How Mutations Have Established New Principles, Pathway

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    Default Immunology, Phenotype First: How Mutations Have Established New Principles, Pathway

    Immunology, Phenotype First
    Ho
    w Mutations Have Established New Priniciples And Pathways In Immunology

    by Bruce Beutler




    Pages: 236
    Publisher: Springer Berlin Heidelberg
    Edition: Jan 2008
    Language: English
    ISBN-13: 9783540752028

    Description



    This monograph deals with the impact of classical genetics in immunology, providing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who don’t fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. “Why bother with classical genetics,” they may ask. “Won’t all genes be knocked out soon anyway?” Or they are intimidated by genetics, with its heavy reliance on model organisms that seem so alien. “What has C. elegans to do with me?” they may ask. “It doesn’t even have lymphocytes.” They may be unaware that the mouse is fast becoming as tractable a model organism as the fly, and that humans may not be too far behind.

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    Default Re: Immunology, Phenotype First: How Mutations Have Established New Principles, Pathway

    Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology (Current Topics in Microbiology and Immunology)
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