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Emerging and Reemerging Infectious Diseases of Nonhuman Primates in the Laboratory Setting

pathvet

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China Veterinary Student
Emerging and Reemerging Infectious Diseases of Nonhuman Primates in the Laboratory Setting
by C. Bailey and K. Mansfield
Veterinary Pathology, 2010, 47(3): 462-481
Abstract:
Despite numerous advances in the diagnosis and control of infectious diseases of nonhuman primates in the laboratory setting, a
number of infectious agents continue to plague colonies. Some, such as measles virus and Mycobacterium tuberculosis, cause
sporadic outbreaks despite well-established biosecurity protocols, whereas others, such as retroperitoneal fibromatosisassociated
herpesvirus, have only recently been discovered, often as a result of immunosuppressive experimental manipulation.
Owing to the unique social housing requirements of nonhuman primates, importation of foreign-bred animals, and lack of antemortem
diagnostic assays for many new diseases, elimination of these agents is often difficult or impractical. Recognition of these
diseases is therefore essential because of their confounding effects on experimental data, impact on colony health, and potential
for zoonotic transmission. This review summarizes the relevant pathology and pathogenesis of emerging and reemerging
infectious diseases of laboratory nonhuman primates.
 
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